The FAO/WHO Joint Expert Committee on Food Additives (JECFA) has established provisional tolerable weekly intakes (PTWIs) for the heavy metals As, Al, Cd, Cr, Cu, Hg, Pb, Fe, Ni, and Zn in fish. The PTWIs are based on the estimated daily intake of the metal from all sources, including fish. The PTWIs are set at levels that are considered safe for human consumption over a lifetime. The FAO also recommends that fish consumption should be limited to 500 g/week. This is to ensure that the PTWIs are not exceeded and to reduce the risk of health risks associated with consuming large amounts of fish.

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