In many developing regions, hypersensitivity symptoms (such as unexplained skin reactions, allergic rhinitis, or fatigue) are often overlooked as minor complaints.

But could these symptoms actually reflect early immunological or psychosomatic responses to environmental or lifestyle stressors?

I wouetld greatly value your thoughts on:

• Could hypersensitivity act as a biomarker or predictor of deteriorating well-being?
• How can we scientifically categorize subtle hypersensitivity signs that don't fit classic allergy models?
• Are there cultural or environmental modifiers that influence the hypersensitivity–QoL relationship?

Looking forward to hearing your insights and suggestions for literature or tools. Thank you!