I am using a Pharmaceutical preparation of Gemcitabine which is reconstituted in saline for use, in animal models and cell function assays. As I do not have storage information beyond one week after reconstitution, I am trying to use it before that by storing at 4 degrees for that week. Please help if you have any experience with storage beyond one week after reconstitution.
Thanks
Dear Mr. Srinivasa Pothula! I guess you might start with an information below:
J Am Pharm Assoc (Wash). 1999 Jul-Aug;39(4):509-13.
Physical and chemical stability of gemcitabine hydrochloride solutions.
Xu Q1, Zhang Y, Trissel LA.
Dear Mr. Srinivasa Pothula! I guess you might start with an information below:
J Am Pharm Assoc (Wash). 1999 Jul-Aug;39(4):509-13.
Physical and chemical stability of gemcitabine hydrochloride solutions.
Xu Q1, Zhang Y, Trissel LA.
Dear Mr. Srinivasa
I think that you should depend on the storage conditions stated on the label of the product available to you as these conditions were determined depending on stability study after reconstitution where the product may degrade into ineffective or lower potency products after that. Extending the period of storage should depend on a study to justify that , otherwise, use it as stated on the label or you may not get the expected and reliable results from your experiment
Regards
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