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28 December 2020 8,302 3 View

How to extract mapped reads for paired-end reads?

I am working with paired-end reads, and want to extract all those reads which map to an assembly. Since its a paired-end reads, I am confused if I should extract reads for which both (forward and...

22 August 2020 3,887 3 View

When is performing temporal convergence necessary in wall-bounded flows?

In CFD, grid convergence study involves both spatial and temporal discretization error analysis. In curved channels, where the fluid experiences centrifugal forces, secondary flows are formed...

11 August 2020 4,683 3 View

How can we tackle with interference of two peaks in XPS?

Dear scientific society, In my XPS results of Ru-zeolite catalyst, there's no carbon however in the spent catalyst there is a chance of carbon deposition. I spent catalyst XPS, Ru 3d3/2 at 284.6...

24 July 2020 4,494 4 View

How to do MD simulation after doing docking with Autodock?

I am trying to find an inhibitor for a protein, and for that purpose, I did preliminary docking using Autodock to find potential inhibitors. Now, I need to check if that docking is stable or not....

10 May 2020 9,563 3 View

How to get drug structure (pdb) from .xml file available on drugbank?

I am working with molecular docking and I want to dock the whole database of human approved drugs over my protein, but for that, I will need PDB file of those drugs. I looked it up over drugbank...

27 April 2020 4,678 2 View

While meshing a pipe for simulation as periodic, is it safe to consider computational domain dimensions used in the case of periodic channel?

ANSYS recommendation states that the size of the computational domain for a straight channel with channel height H is taken as 4H in the stream-wise direction and 1.5H in the span-wise direction....

08 January 2020 6,389 3 View

How to combine two illumina reads?

I am working on WGS, and I have generated two pairs-end reads (total 4, two forward, and 2 reverse)(the difference is in their DNA purification method). Now, I want to combine these two pairs of...

27 November 2019 3,744 4 View

How do i design slabs on the first floor of a building with a circular atrium?

So the first floor of the picture should give an idea. I'm talking about concrete slabs. Thank you.

03 May 2019 6,308 2 View

What would be the cost of thermoinetic mixer?

more specifical ----model MH - 50H can you give me its specification adn prize and where can i buy i india

01 August 2018 2,133 1 View

Logistical regression using SPSS for a dichotomous dependent variable, with an independent variable of 1, 2, 5 and 10 seconds?

I have an experiment with 28 participants The independent variable is the times 1, 2, 5, and 10 used as the cross hairs during a task These 4 times were tested using 4 different blocks, each...

03 March 2021 9,692 2 View

What is the procedure to determine the permeability of concrete?

can anyone help me in this, it will help me with my research work

01 March 2021 834 3 View

How to classify strictly upper triangular matrices by similarity?

Let F be a field. Consider U, the set of n times n strictly upper triangular matrices in F. For X, Y in U, we call them similar if there exists some S, which is non-degenerate and upper...

01 March 2021 2,957 8 View

How could I process data in RCT to include it in meta-analysis?

I'm in the process of doing a meta-analysis and have encountered some problems with the RCT data. One of my outcom is muscle strength. In one study, I have three different measurements of muscle...

25 February 2021 7,603 3 View

Is it mandatory to specify Subjects Combinations in Generalized Linear Mixed Models (SPSS)?

Hi all, I have data with two levels: lets think of the classic example of students and schools. When running the analysis in SPSS and selecting the Random Effects, we can select (we can or we...

24 February 2021 7,379 4 View

How can I generate random samples from Bingham distribution in R? How can I construct those symmetric matrices?

in the function rbingham(n,A) in R software how can I construct that A (symmetric) matrix?

24 February 2021 3,528 3 View

ANCOVA controlling baseline in RCT - how to perform power analysis and sample size estimation?

Hi, I have a simple question. I am hoping to perform a power analysis/sample size estimation for an RCT. We will be controlling for baseline symptoms, and using post-treatment or change scores as...

19 February 2021 2,648 23 View

What will happen when we assume an upper bound of OFV lower than the global minimum OFV ?

if we assume 20 is the upper bound of an objective function (OF) based on permutation a square matrix (nxn) , The minimum value of the OF=22, then we run a random operator to compute the OF by...

14 February 2021 6,056 5 View

Pseudo random number generator in Matlab code ?

i want to implement pseudo random number generator in matlab ...i request to every one if someone have code these PRNG share with me SplitMix Permuted Congruential Generator (PCG) Random...

14 February 2021 6,828 7 View

How to model in HFSS or FEKO Free Space Material Characterization?

I am having trouble setting up this problem in HFSS or FEKO. In HFSS, I've tried both FEM and FEBI-IE solvers. With FEKO, I've tried it's MoM solver and default settings. I am would like model...

09 February 2021 375 2 View