Can you tell me about the connection between variability heart rate and bipolar depressive disorder (or pharmacoresistant unipolar depression)? I would be very thankful for the publications you know of about this topic which applied fractal and nonlinear measures, apart form frequency analysis. I know of some finding about the link between the outcome of ECT and VHR in depression, but the sample was small. We are trying to understand our data and it is difficult to find newer publications apart from Goldberger, Pincus, Costa et al on nonlinear measures illustrating that connection.
Thank you
Michael Uebel, thank you very much! I was aware if just one of those studies you sufested, thanks.
- Moon E, Lee SH, Kim DH, Hwang B. Comparative study of heart rate variability in patients with schizophrenia, bipolar disorder, post-traumatic stress disorder, or major depressive disorder. Clinical Psychopharmacology and Neuroscience. 2013 Dec;11(3):137.
- Chang HA, Chang CC, Kuo TB, Huang SY. Distinguishing bipolar II depression from unipolar major depressive disorder: differences in heart rate variability. The World Journal of Biological Psychiatry. 2015 Jul 4;16(5):351-60.
I was interested in your question and found these references in about 30 seconds on Google Scholar. Asking on Researchgate is no substitute for literature searching. If I really wanted an answer to this question, I'd be off noodling around PubMed and Scholar, and I'd put the key terms into JANE: http://jane.biosemantics.org
JANE is a semantic search engine, and good for finding papers that don't turn up on regular searches
Ronan Michael Conroy, thank you for your reply. It is not that I am lazy to do literature research myself, I already did some. But did not find any which are using fractal and nonlinear analysis, that I am not aware of already, like Goldberger, Pincus, Costa et al...The thing is we already use some nonlinear measures of entropy and the interpretation and understanding of nonlinear measures is something which can differ from study to study. Almost none of those studies use the same measures, they use jus frequency analysis. Maybe I was not asking the question like I should, I usually get helpful suggestions from colleagues here (isn't it one of the main purposes of Research gate?). Also we do not have access to the same databases, so an interested researcher can help, not only with a search but with his own experience. Thank you for the link to Jane, too.
Milena Cukic – I hope you didn't think I was reprimanding you! I wasn't clear on your question, and hoped that you weren't trying to substitute RG for a search. I must apologise if I offended you!
My advice would be to make contact with the authors of the original article. And also put the key terms in your question into JANE to see who else is publishing in these areas. I would think that using JANE to search for methodological papers might yield people who are working in the area but not in your application.
Ronan Michael Conroy, no worries, I already used Jane to find something. And I edited the question, because I realized it was not clear enough.
Regards,
Milena
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