Hi everyone,
does someone know the chemical structure of midori green? I would be also happy about references.
Thank you in advance
Tobias
My understanding is that this image represents four molecules that were isolated at the graduate School of Pharmaceutical Sciences at Chiba University in Japan by a group of scientists that includes Assoc. Prof. Midori. The molecules are 1) Parviflorene F, 2) Branisianin D, 3) Dihydroflavonol BB-1, and 4) Fuligocandin. I don't think any of these are the same molecule that is used in the nucleic acid stain by the brand name of Midori Green. I'm guessing that this is a trade secret and the structure has not been published. The molecule is described as a large molecule that does not get absorbed by living tissue (one of the safety features) but the company doesn't even publish the molecular weight as far as I can tell.
Hi Tobias, there is a structure of midori green on google images, but I can't open it.
https://www.google.com/search?tbm=isch&sa=1&q=%22MIDORI+GREEN+stain%22+structure&oq=%22MIDORI+GREEN+stain%22+structure&gs_l=img.3...15282.19788.0.20316.11.10.1.0.0.0.210.1191.4j5j1.10.0....0...1c.1.64.img..0.0.0.FxSNr6t3LEI#imgrc=_
(Midori green dna stain msds)
My understanding is that this image represents four molecules that were isolated at the graduate School of Pharmaceutical Sciences at Chiba University in Japan by a group of scientists that includes Assoc. Prof. Midori. The molecules are 1) Parviflorene F, 2) Branisianin D, 3) Dihydroflavonol BB-1, and 4) Fuligocandin. I don't think any of these are the same molecule that is used in the nucleic acid stain by the brand name of Midori Green. I'm guessing that this is a trade secret and the structure has not been published. The molecule is described as a large molecule that does not get absorbed by living tissue (one of the safety features) but the company doesn't even publish the molecular weight as far as I can tell.
Thanks a lot for your answers! I think you are right Ron, I had the same impression that the structure is just not yet published. Thus, I think the carcinogenity and mutagenesis values given by the company maybe have to be proven and compared to other DNA stains in an independent study. In such a study chemical structures could be published as well.
Maybe a good idea for a publication?
Maybe a comparison of Midori Green with SYBR Green and PicoGreen similarly to this paper. http://nar.oxfordjournals.org/content/32/12/e103.full
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