How to handle studies which report perfect effect sizes in a meta-analysis using Pearson's r?

I'm in the process of updating a meta-analysis and in one of the new studies, effect sizes are reported as Tau-U. Two of the effect sizes are reported as Tau-U = 1.00. I am using Andy Field's...

24 February 2021 2,265 3 View

How to model in HFSS or FEKO Free Space Material Characterization?

I am having trouble setting up this problem in HFSS or FEKO. In HFSS, I've tried both FEM and FEBI-IE solvers. With FEKO, I've tried it's MoM solver and default settings. I am would like model...

09 February 2021 375 2 View

Statistical Test for Single Group over Multiple Conditions & Different Time Lengths?

I have a dataset with an unusual configuration and was hoping for guidance on choosing a method to test for changes in mean. For context, this is operational data tracking vehicle arrivals at 10...

20 January 2021 4,429 4 View

How long does MQAE solution last once prepared?

I am wanting to prepare a small quantity of MQAE solution. Once prepared, how soon should it be used? How fast will it degrade? Is there a way I can store a leftover amount for future use? Are...

20 December 2020 1,416 3 View

Why do many stock buffers ask you to adjust pH and then add more water?

Could someone please explain why many stock buffers ask you to adjust the solution's pH and subsequently increase the volume to a set amount? For example: Add 500g of powder X to 800mL of...

09 December 2020 1,882 3 View

How to estimate sample size when you think the effect size will be reduced (compared to previous studies)?

Hi, I am planning a follow-up experiment to a previous study and have a question about estimating sample size: For the sake of simplicity, the previous study showed that Condition 1 had more...

19 November 2020 7,948 6 View

What is angular velocity of projection of uniform circular motion?

12 November 2020 481 5 View

Peptide solubility in DMF (n,n-dimethylforamamide)?

I am looking to dissolve a suite of "acidic" peptides for, ultimately, a validated LCMS assay. Using DMF as an initial solvent (20% of final volume) but some peptides precipitate when aqueous is...

15 October 2020 9,171 1 View

How do crush foraminifera for d18O analysis?

I am looking to combine and crush 5 foraminifera to create a homogeneous carbonate powder that I will then be sending out for oxygen analysis. Does anyone have any good methods to make these...

14 October 2020 8,128 7 View

Troubleshooting co-IP from a small amount of brain tissue?

I am looking to perform a co-IP; however, I am using a very small amount of tissue to begin with from region specific microdissection in mice (2-3 300um sections per animal). I am concerned that...

07 October 2020 8,937 3 View

Which isomer of xylene do you use in hystology ?

Which isomer of xylene do you use for the preparation of histological tissue sections - meta para or ortho?

02 February 2021 833 4 View

What defines the time it takes to disconnect a molecular switch?

I have been thinking about a material that was made 6 months ago, which is a tetramethylsiloxane linked to a thiazolidinedione and finally to a naphthalene, but I can't find the original paper (if...

30 December 2020 5,347 1 View

Is RID-20A(Refractive index detector) from shimadzu suitable for stepwise elution in HPLC?

I apply mobile phase stepwise elution in HPLC to separate glucose isomerization to desired fructose. However, I got unreasonable result showing reaction selectivity of fructose is larger than 1. I...

28 August 2020 3,278 3 View

Am doing FITC coupling with APTES for FITC-APTES conjugate using ethanol as solvent. After 12h reaction, I got a precipitate, Is it normal?

I used FITC Isomer I and ethanol and APTES under argon. The precipitate is bright orange. I want to use this for synthesis of nanoparticles (dye conjugated) and the precipitate will not help in...

08 September 2019 2,138 2 View

What kind of isomerism shown by steroid?

I am looking for isomerism of steroids, can you share details, books, articles, reviews discussed on steroids isomerism in details Thanks Raj Kumar

08 September 2019 3,645 3 View

How to confirm Leve and Dextro optical rotation of stereo isomer?

Currently, I'm working in stereo isomers. I have trying to synthesis stereo isomers. My problem is how can I confirm their optical rotation in experimentally. Please let me know if you have any...

09 October 2018 5,128 5 View

How to stabilize cis-oxyresveratrol ?

Normally oxyresveratrol found in trans form. But we can convert trans form to cis form by photochemical transformation. However the stability of cis form is too less. It can easily converted to...

08 September 2018 553 0 View

Antibody against fluorescein isothiocyanate, isomer I (FITC)?

Hello, Anybody can recommend the reliable antibody that binds to the fluorescein isothiocyanate and works in frozen brain sections?

06 July 2018 9,491 0 View

How do you calculate recoveries from GC/MS samples that contain isomers that undergo isomeric conversion under experimental conditions?

Hello. I have been working on a study that is exposing N27 and SH-SY5Y cells to alpha-cypermethrin, a combination of two isomers. It seems to generate two peaks on achiral columns. We have...

05 June 2018 6,182 1 View

How to find out exact percentage of the individual isomer in racemic mixture?

Recently I synthesized the 3-substituted 3-amino oxindole starting from ketimines derived from isatin. After close examination, I come to know that the final product is in the racemic form. I want...

04 May 2018 7,820 3 View