I am wondering if anyone has had success with in vitro polarization (via cytokines) of Jurkat cells. My goal is to understand the affect of a drug on Treg induction and differentiation. I understand that this would be reasonable using human/mouse primary T cells, however this may not be practical and or feasible in my case, at least for now. I would like to first explore the effect of this drug on T cell activation/differentiation using Jurkat cells. I am having trouble finding literature on this topic. Thanks in advance.
Dear Ben!
You also look at following article:
Article Molecular pathway profiling of T lymphocyte signal transduct...
Hi Ben, here is an earlier paper from 2012 on the topic:
Article Molecular pathway profiling of T lymphocyte signal transduct...
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