After exposing rats to low fructose water(10%) for 2 wks and a single intraperitoneal injection of STZ (55mg/kg bw), to induce T2D, I want to compare the hypoglycaemic effect of my crude plant extract with a known standard drug.
Use 150mg/kg b.w. of metformin HCL as std ref. against 150mg/kg b.w. of your extract as well as other variable doses of your extracts with increaments / decrements of 50mg/kg b.w.