Hello, I want to make a synbiotic microbead which contains probiotic and prebiotic in gel matrix. Without extra nutrient, probiotic is expected to grow inside of microbeads by consuming the prebiotic. I have tested that before gelation, probiotic can grow in prebiotic/gel matrix solution, but after gelation, probiotic cannot grow inside of beads anymore.
I do not know why, and very appreciate if anyone can provide some suggestions. Thank you.
Check https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622781/
Also check https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648921/
Hello, Probiotics grow in anaerobic conditions when prebiotics are available. therefore, I think it's be better if you make it lyophilized synbiotic microbeads, In this way, you have guaranteed high Viability of probiotics and no consumption of prebiotics.
- Badges
- Science topic
- Similar topics
- Biological Science
- Microbiology