I suspect that adult rats developmentally exposed to manganese suffer from postural deficit that may have contributed to their poorer reaching and grasping performance on the staircase test of food retrieval. What would be a sensitive behavioral method to detect impairment in posture and limb coordination?
Article Early life versus lifelong oral manganese exposure different...
The postural reflexes and relevant musculature have been studied most extensively in the cat. Search there and you'll undoubtedly come across a useful paradigm or two, either in gross behavior or electrophysiology.
Thanks Cyrus for your response. I was looking for a behavioral correlate in another test of motor coordination. What do you expect from methylphenidate treatment on skilled motor behavior?
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