I am planning to use Two-Way Orthogonal Partial Least Squares (O2PLS) to analyze two kinds of omic data ( transcriptmic and metabolomic).
My experiment is like this,I have 2 experimental groups and one control groups.
for my transcriptmic data , I have 3 repilcates for each group; and for my metabolomic data, i have 9 replicates for each group. My question is whether I can use O2PLS method to integrate omic data with different replicates?
is there R codes to deal with this problem
Thanks so much in advance!