02 February 2023 0 4K Report

I am planning to use Two-Way Orthogonal Partial Least Squares (O2PLS) to analyze two kinds of omic data ( transcriptmic and metabolomic).

My experiment is like this,I have 2 experimental groups and one control groups.

for my transcriptmic data , I have 3 repilcates for each group; and for my metabolomic data, i have 9 replicates for each group. My question is whether I can use O2PLS method to integrate omic data with different replicates?

is there R codes to deal with this problem

Thanks so much in advance!

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