I have to make some tests for independence between several composite variables, such as BPRS-Total, BPRS-Negative, BPRS-Positive etc., and a number of explanatory variables. The problem is that these composite variables have too many levels. My questions are, can I reduce the levels by taking the average of the items included, will it be correct? And is there a standard system of cut-off values defining the patient's condition based on BPRS (24) total?

Thank you in advance!

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