Can I carry out an Appel reaction in DMF, because my substrate is very polar and insoluble in DCM?

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Adel Amer

DMF/PhH mixture has been used for Appel reaction. Plz., see

---Steven V. Ley, J. Chem. Soc., Chem. Commun. 1982, 1252.

reported @ http://www.synarchive.com/syn/196

Good luck

Nidal Saleh

THF, ether-ACN, DMF-benzene, but in the last strategy high exess of CBr4 is required, ilor you have to use Br2 which is quite dangerous