Frank Doering

4 Questions 2 Answers 0 Followers

Questions related from Frank Doering

Can I carry out an Appel reaction in DMF, because my substrate is very polar and insoluble in DCM?

Appel reaction in DMF?

05 February 2014 2,290 2 View

Does N-acylation of cysteinmethylester work with an acid-NHS-ester ?

I want to carry out an N-acylation of cysteinmethylester with the succinimidyl-ester of boc protected ß-alanin. Does it work? I do not know about the behavior of the sulfhydryl-group.

14 July 2012 214 2 View

Stability of N-BOC-group during RP-chromatography with eluent ACN/H2O/TFA?

I want to purify a compound which contain a BOC-protected sec. amine with RP chromatography and eluent ACN/H2O/(1-2% TFA). Can anyone tell me about the stability of the BOC-group during the...

06 July 2012 4,614 9 View

Separation of nanoparticle and IgG

We have coated IgG (goat anti mouse) on 70 nm Silica nanoparticles. Now we want to separate the unbound IgG from the nanoparticles with size exclusion chromatography. What kind of gel would you...

29 June 2012 9,894 2 View