Can human recombinant BDNF (commercially available) be used for stimulation in rats and mice?

06 June 2013 1 3K Report

Commercially available BDNF is human recombinant protein. Can you use it for stimulating primary neuronal cultures of mice and rats? If yes, what is the basis of this cross species activity?

Tomi Rantamäki

Mature BDNF protein sequences are identical among humans, mice and rats.

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