There is evidence for emergence of resistance in carried bacteria following antibiotic use in primary, secondary and tertiary care settings. And for example, the pneumococcal conjugate vaccine reduces the prevalence of resistant pneumococci in carriage.
Can community/population carriage of resistant bacteria predict the incidence of invasive disease by resistant bacteria?
Any takers, I would really appreciate your insights/feedback. Thanks
Thank you, Omar Okasha.
I have seen the Weinberger paper because I also have a side interest in modeling changes to invasive pneumococcal disease following vaccine introduction using carriage data. I am not sure this model would directly apply to the incidence of resistant IPD following carriage of resistant pneumococci but it is an interesting question to tackle if the data to do so is available.
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