Actually, I want to know about the modelling of cancer cell.
I need to know about the evolution of nonlinear term in that model.
Dear Sabarathinam,
I believe that you are pose a completely wrong question. Cancer is a biological fact, with great complexity, heterogeinity and specificities, even whithin a "same class of cáncer type". There are not cancers, but only patients with cáncer. Mathematical Models are formal tolos to deal with specific, but partical apects of complex or simple but not well understood situations). Models are designed to answer more or less specific questions. There are not "universal" models for cancers. Mathematical models are not pyshical laws, even when non-linearity is often present in many biological situations given that living cells are termidinamically open systems....In brief, you sould model the some particular type of reality. Your model cannot be a photocopy of the reality. You have to do, some type de approximation or simplification. Non-linear terms will appear naturally in this way....! Best,
Daniel .
see http://www.ikar.udm.ru/sb/sb29-1.htm - Коллоидная природа рака. The colloidal nature of the cancer.
and - http://eng.ikar.udm.ru/sb/sb46-1e.htm and experience and theory http://ikar.udm.ru/files/pdf/ikar_2015_en.pdf
Regards, VS
http://ikar.udm.ru/files/pdf/ikar_2015_en.pdf
http://www.ikar.udm.ru/sb/sb29-1.htm
http://eng.ikar.udm.ru/sb/sb46-1e.htm
Hi, you can see some publications of Bratus Alexander here (ResearchGate) and references in them. Best regards, Yuri.
Hi, for nonlinear analysis, you can see some publications of Kassara et al., as:
Kassara K. . A set-valued approach to control immunotherapy. Mathematical and computer modelling , 2006
http://max.book118.com/html/2015/0317/13409269.shtm
I think proliferation of cancer cell just like the Infectious Diseases
look into cancer cells as cheater individuals infiltrating into a cooperative society (formed of healthy tissue)
Dear Sabarathinam,
I believe that you are pose a completely wrong question. Cancer is a biological fact, with great complexity, heterogeinity and specificities, even whithin a "same class of cáncer type". There are not cancers, but only patients with cáncer. Mathematical Models are formal tolos to deal with specific, but partical apects of complex or simple but not well understood situations). Models are designed to answer more or less specific questions. There are not "universal" models for cancers. Mathematical models are not pyshical laws, even when non-linearity is often present in many biological situations given that living cells are termidinamically open systems....In brief, you sould model the some particular type of reality. Your model cannot be a photocopy of the reality. You have to do, some type de approximation or simplification. Non-linear terms will appear naturally in this way....! Best,
Daniel .
I fully share Daniel's opinion.
If cancer would have been actually "modelled", we would see much higher cures of cancer patients ...
I also fully share Marc's opinion. Indeed, certain very restrained aspects of cancer cell biology can be mathematically modelled (but only approximately), such as the cell cycle, but never the whole biological behavior of a cancer itself.
Best regards,
Robert
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