Are there any other lab based methods apart from X-RAY by which I can tell that the hydrogel beads (for oral drug delivery) which I have prepared are radioopaque?
I want to make gastroretentive drug delivery system for drugs which is retained in the stomach by using BaCl2 and MgSO4. For validating the dosage form in lab conditions i am asking whether there are any other techniques apart from X-Ray so that i can come to know that the beads which i have made are having radio-opaque characteristics which makes these beads easy to trace in IN-VIVO conditions.
Using X-ray phase contrast imaging technique you can locate, image and trace the movement of the beads In-vivo in a small animal like mouse. What is the typical size of the bead and typically how much time it retains in the stomach.