I am trying to do the statistical analysis of bacterial growth in two different media to see the difference. In the graph it looks different but I would like to use some statistical method. Spline regression model in R has been used by some reascher, but I did not understand how to develop the codes for it. Can anyone help me to figure that out.Thank you
Hello. A good reference for splines is Numerical Recipes, although they deal with C and Fortran rather than R. Splines will smooth your data, assuming it is 1-D (just x and y values). I don't see how they will provide a statistical analysis, unless you call a regression line a statistical analysis. Maybe someone who knows more about this can clarify.
It is definitely a late answer, but please look over sme package from Maurice Berk and his dessertation: http://cran.nexr.com/web/packages/sme/vignettes/Tutorial.pdf The approach might requires some custom code adjustment to your study design.
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