Dear Abhay Mishra

You want to develop a formulation but for which you are looking for a specific and standard formula, that this? Well, the choice depends on a few factors, such as: what type of wound (burn; bacterial infection, anyway...), cream or ointment option as standard (ointments are more resistant to water and offer a better protective layer for the skin. They are indicated for more superficial problems. Creams, on the other hand, have a faster penetration than ointments). However, generally, to prepare a standard formulation is added the % of the active ingredient (for example 5%)(w/w), thus, you add 5 g of active principle into 100 g of simple ointment/cream base. Briefly, this is it.

I hope this helped you.

Regards,

The most neglected aspect of wound healing is cellular oxygenation and nutrition. Wound-healing fibroblasts need lots of oxygen and food, so that tissue perfusion and delivery of the glucose and oxygen to the cells is the key. Plus, hypercarbia is needed to release oxygen from the hemoglobin molecule via the Bohr Effect. CO2 enables every aspect of the mechanism of oxygen transport and delivery. This is basic physiology. Today’s doctors have totally forgotten the powerful therapeutic effects of Carbogen, which were well understood and accepted in the 1930’s. I was astonished when I learned of this during my investigation of anesthesia history. Read the attached paper that reviews the pathophysiology of carbon dioxide. Breathing Carbogen (a mixture of 5% carbon dioxide and 9% oxygen in a pressurized tank) is the most convenient and effective approach, but Big Pharma has wrapped its tentacles around everything that involves CO2 treatments, so that Carbogen must nowadays be special-ordered from the Airgas Corporation and costs $500.00 for a small tank. This is insane, because both oxygen and carbon dioxide are cheap. The price is obviously rigged to discourage utilization. Another approach would be to enclose the patient in a SCUBA “dry suit” and inject carbon dioxide inside the dry suit. The CO2 is absorbed directly through the skin, and will slightly exaggerate CO2 blood levels, which will release nitric oxide from the capillary endothelium, reduce microvascular flow resistance, improve tissue perfusion and enhance the release of oxygen from the hemoglobin molecule via the Bohr Effect so as to elevate tissue oxygenation and promote wound healing. There is no danger because CO2 stimulates respiratory drive and prevents excessive CO2 accumulation within the body.

Thank you so much Diorge Marmitt and Lewis Coleman for answering my question. I am also looking for a standard natural base formula. Can you suggest which natural base and in which %/ratio would be better to make 100g cream?

Try the silver ions

@Ernesto Gadsden, will you please elaborate how or detail methodology?

Abhay