Hello all. I have been searching for research in coffee consumption, tea or any other substance in adults with ASD, to see if the effect perceived by neurotypical individuals is the same in ASD individuals. Can someone help me with this?
Ghanizadeh A. Possible role of caffeine in autism spectrum disorders, a new testable hypothesis. J Food Sci. 2010 Aug 1;75(6):ix. doi: 10.1111/j.1750-3841.2010.01760.x. PMID: 20722962
Lai MC, Kassee C, Besney R, Bonato S, Hull L, Mandy W, Szatmari P, Ameis SH. Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis. Lancet Psychiatry. 2019 Oct;6(10):819-829. doi: 10.1016/S2215-0366(19)30289-5
Ressel M, Thompson B, Poulin MH, Normand CL, Fisher MH, Couture G, Iarocci G. Systematic review of risk and protective factors associated with substance use and abuse in individuals with autism spectrum disorders. Autism. 2020 May;24(4):899-918. doi: 10.1177/1362361320910963
Arnevik EA, Helverschou SB. Autism Spectrum Disorder and Co-occurring Substance Use Disorder - A Systematic Review. Subst Abuse. 2016 Aug 17;10:69-75. doi: 10.4137/SART.S39921.
There are some things published, but no Meta-analysis, Systematic Review or any Publication on research in this regard, with a Control Group, Double blind, etc. that indicates or demonstrates that such "minor" stimulant substances (not psychoactive psychostimulant drugs such as amphetamines or cocaine, for example) have some positive or negative influence on ASD, at normal doses of "common use", since a MEGADOSIS would have the negative effects they have on any subject, whether they are affected by ASD or not.
Thanks for the reference. I will search for it. What i am looking for is if such psychoactive substance of common use have no or different effect in ASD than NT Population.
I would recommend looking into how metabolism and ASD are related. Here's a good starter paper for you:
Ming X, Stein TP, Barnes V, Rhodes N, Guo L. Metabolic perturbance in autism spectrum disorders: a metabolomics study. J Proteome Res. 2012 Dec 7;11(12):5856-62. doi: 10.1021/pr300910n. Epub 2012 Nov 9. PMID: 23106572.