No, these all are calculated against a gold standard.

Thank you very much Mehmet for response!

Hello Narjes,

It's possible to create a gold standard group  using a statistical technique called Latent Class models.

See:

Pan-ngum et al 2013 Estimating the True Accuracy of Diagnostic Tests for

Dengue Infection Using Bayesian Latent Class Models

There are some concerns about it but, it could give you a idea about your tests

Hello Moreno,

thank you very much for response.

before I wrote email to  Dr. Garrett who write an article about Latent  Class models. she said it is not possible for your work.

Regards