Hi,

I am having difficulty with a few questions in my graduate course project after attempting to answer them myself. I've attached the group A and B sequences. I've also attached my reasoning showing that these groups are homologs as well as the phylogeny.fr phylogentic tree of A and B sequences. They are in the document: "extras." This can help with questions 1-3:

Question 1: I need sequence Logos of around 15 aa in length for the two best signature motifs of Group A sequences. I need to do the same for Group B sequences. I've done logos but I don't understand what this is asking.

Question 2: Do groups A and B have the same function? Are any of these sequences paralogs? - Explain. Again, I'm confused. I know what paralogs are. Am I supposed to look at the function of each protein sequence individually and then compare? That can't be right as it would be grossly inefficient.

Question 3: Find the structure of one member of this family and post the PDB number. -I've run blastp searches on several proteins and they are all hypothetical, most of them ATP-binding. Because of this, there's limited annotation making it hard for me to find a PDB #.

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