Hi,
I have a Transcription factor binding site identificated. And I got a track from Drosophila genome with all the locations of this binding site. I would like to compare the acumulation of my binding sites with other preexisting tracks of other factors and see if there is any kind of correlation.
My knowledge of bioinformatics is very low and I don't know how to perform this, so I appreciate any kind of help.
Thank you in advance.
Jose.
I would recommend this website:
http://rosalind.info/problems/list-view/?location=bioinformatics-textbook-track
I myself a learner, this one gives you plenty of practices and homework for new beginners.
Suggested reading
Self Learning of Bioinformatics Online: Online learning,tutorial,Video,Blog,Social Media Kindle Edition-by Ajit Roy (Author).
https://www.amazon.com/dp/B00ZVEMX00
If you want to compare tracks of TF binding sites, the easiest is maybe to download their genomic coordinates (chr, start, end, possibly also strand and score) in the bed format and then to search for any coverage of one track by the other(s). One of the popular tool to do this is the bedtools suite (http://bedtools.readthedocs.org/en/latest/content/bedtools-suite.html), which is also available directly on GALAXY (https://usegalaxy.org) if you're not comfortable with command line. Good luck!
- Badges
- Science topic
- Similar topics
- Computer Science and Engineering
- Bioinformatics