The evidence is mixed and variable over the decades. More recently, evidence suggests mental illness can be associated with having an hysterectomy.

Case Study

A lady, aged 54 had an hysterectomy in August last year. Her mental health has deteriorated following the procedure. There is a familial history of the same or similar occurrence. For example, the lady, her mother and grandmother developing mental illness post hysterectomy. The presentation, includes depression, anxiety including panic and paranoia.

Questions:

Is there any evidence for a genetic link in the family?

Is there any evidence of increased risk of developing psychosis such as paranoid thinking?

Is there any evidence that HRT or hormone treatment can improve symptoms?

Any evidence or debate would be appreciated.