Dear all, I advise you to search within RG as Dr. Pierluigi Traverso suggestion. No one Can denay the nanoparticles toxicity but only when exposed to. Nanoparticles are applied in other fields rather than health care and drugs, exemple solar panels, agriculture, and so on. Research is still going on to find ways to coat nanoparticles with less harmfull materials so that they will be acceptable when administrated to the body. My Regards

Dear Dr. Hem C. Joshi,

as said in other, similar question here in RG, let me suggest you take a look at the following, recent scientific papers:

-Health hazards of nanoparticles: understanding the toxicity mechanism of nanosized ZnO in cosmetic products

Vimala Devi Subramaniam, Suhanya Veronica Prasad, Antara Banerjee, Madhumala Gopinath, Ramachandran Murugesan, Francesco Marotta, Xiao-Feng Sun & Surajit Pathak

Drug and Chemical Toxicology Volume 42 - Issue 1 (2018)

Available at: https://www.tandfonline.com/doi/abs/10.1080/01480545.2018.1491987

-Importance and health hazards of nanoparticles used in the food industry

Bazila Naseer, Gaurav Srivastava, Ovais Shafiq Qadri, Soban Ahmad Faridi, Rayees Ul Islam and Kaiser Younis

Nanotechnology Reviews, Volume 7: Issue 6 (2018)

Available at: https://www.degruyter.com/view/journals/ntrev/7/6/article-p623.xml?language=en

-The engineered nanoparticles in food chain: potential toxicity and effects

A. M. Maharramov, U. A. Hasanova, I. A. Suleymanova, G. E. Osmanova & N. E. Hajiyeva

SN Applied Sciences volume 1, Article number: 1362 (2019)

Available at: https://link.springer.com/article/10.1007/s42452-019-1412-5

-Chapter 5 - Risks and toxicity of nanoparticles and nanostructured materials

Kei X.Tan, AhmedBarhoum, SharadwataPan, Michael K.Danquah

In Emerging Applications of Nanoparticles and Architecture Nanostructures

Current Prospects and Future Trends -Micro and Nano Technologies Pages 121-139 (2019)

Available at: https://www.sciencedirect.com/science/article/pii/B9780323512541000051

Best regards, Pierluigi Traverso

Dear all, I advise you to search within RG as Dr. Pierluigi Traverso suggestion. No one Can denay the nanoparticles toxicity but only when exposed to. Nanoparticles are applied in other fields rather than health care and drugs, exemple solar panels, agriculture, and so on. Research is still going on to find ways to coat nanoparticles with less harmfull materials so that they will be acceptable when administrated to the body. My Regards

Health Risks Of Nanotechnology: How Nanoparticles Can Cause Lung Damage, And How The Damage Can Be Blocked. Summary: ... However, concerns are growing that it may have toxic effects, particularly damage to the lungs. Although nanoparticles have been linked to lung damage, it has not been clear how they cause it

Dear all, Dr. Fares Khalifa, may be lung is not as sensitive as brain and the nervous system to the presence of nanoparticles, mainly those metals based. Generally, their irreversible sorption and the ability to breakthrough most membranes are the main mechanisms behind their destructing effects. My Regards

following

Following

Hem C. Joshi

There are safety rules when working with any substances. First of all, the maximum permissible concentration of nanoparticles. The second is respirators. Then there will be no risks. There are other features, for example, nanoparticles of some metals are pyrophoric. During storage, they spontaneously ignite at room temperature in dry form. Typically manufacturers report unexpected properties.

Please go through the following RG links.

Article Nanomaterial exposure, toxicity, and impact on human health

Article Potential Health Impact of Nanoparticles

Please have a look at the following links:

https://en.wikipedia.org/wiki/Health_and_safety_hazards_of_nanomaterials

Article Nanoparticles, human health hazard and regulation

Please follow the link below:

Article PAMAM Nanoparticles Promote Acute Lung Injury by Inducing Au...

In the health science, nanoparticles can cross the cell membrane and enter into the cell and may cause infection. So, during work with nanoparticles have to take safety measure for preventing the entrance of nanoparticles through the oral and nasal cavities. Thus, there is health risk during the synthesis/manufacturing the nanoparticles.