I think your opinion is a valuable one. some researches done similar work. we did in our previous research, too. but we use novel method in Ultrasound images. Local histogram range based image segmentation method(LHRI) can be useful in this manner. although its cost function should be change based on your goal. I hope to be useful this point of view.
other 3 tecniques are photon counting mammography and PEM positron emission mammography and tomosyntesis mammography. About this last tecnique there many papers in literature, not the same for PEM and Photon conting mammography