I would like to know if there are any examples where the HOMFLY polynomial fails. Like two knots having the same polynomial when they shouldn't, or having different ones when they should be the same (this one is not possible I think, since then HOMFLY shouldn't be called invariant any more), or maybe chirality issues. Both Alexander and Jones have their breakpoints, so I assume HOMFLY does too.

What I've found until now is that we can not prove that HOMFLY polynomial is not perfect, but it is not likely to be perfect. I just wonder if anyone found a point where it fails, that I couldn't, an example that proves it wrong.

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