For example, if MIC for a bacterium is 0.1 ug/ml in a particular media(7H9). Would it have same MIC in solid media(7H10)?
It can differed a little because the antbacterial substance diffusion was more in liquid broth than in solid media. Also molecular size of the compound is of certain effect
It will not be the same due to the different reasons. In many cases the MIC obtained by liquid medium will be lower than that of solid medium, however, it depends on type of bacteria under investigation. The attached literature could help:
Theoretically, MIC should be the same, because the network formed by agar is pretty lax and there are no differences in diffusion. The only explanation to what I'm thinking is the better aerobic conditions in the case of agar culture (because the bacteria grow on the surface of agar in this case) and MIC is higher for agar dilution method. For aerobic bacteria, of course. For anaerobic bacteria the cells should be incorporated in agar.
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