In cosmology, the rest frame for the cosmic microwave background (CMB) appears to be a preferred frame of reference. For example, galaxies tend to have an average speed of zero relative to their local CMB rest frame. If an observer is traveling at a relativistic speed relative to the local CMB rest frame, the galaxy density would not appear homogeneous in all directions. Also there would be a substantial CMB anisotropy (unequal photon pressure) which opposes motion relative to the local CMB rest frame.

Now, ignoring the anisotropic effects of the CMB, is there any reason to believe that the laws of physics would not be the same in all frames of reference? For example, if a fundamental particle has relativistic kinetic energy exceeding Planck energy (about 2×109 J), then its de Broglie wavelength viewed from the CMB rest frame would be less than Planck length. Is this possible? Is it possible that experiments conducted in such an extreme frame of reference would find noticeable differences in the laws of physics? For example, would QED and QCD operations which depended on virtual particle creation and destruction be affected?

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