Are 5-HT1A receptors located on hippocampal interneurons?

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How to increase simulation box size?

We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...

08 August 2024 4,842 0 View

When flooding is occured in Cauvery delta region and average flooding duration in this region?

When flooding is occurred in Cauvery delta region and average flooding duration in this region?

24 October 2023 4,189 0 View

Any laboratory which provides outsource service for phytochemical bioactive compound isolation from rhizome of a plant in Malaysia?

Helo all, I am a researcher at Malaysia. Currently, I am looking forward for a laboratory which provides outsource service for phytochemical bioactive compound isolation from rhizome of a plant....

12 June 2023 7,075 0 View

What software can be used to dock metals ions like gold, silver with proteins?

we have doped metal ions like gold, silver with organic molecules. the doped molecules are to be docked with proteins. kindly suggest a software for it

21 March 2023 3,682 2 View

What MoCap technology suits best for Tracking an Object over a large Area?

We are looking for tracking (6Dof) a rigid object over a large area (60mx60m) at atleast 50Hz update rate which could guarantee atleast 1mm resolution. We are considering Vicon, Qualisys, Motion...

13 March 2022 8,027 4 View

What is the Best technique for Object Tracking over a Large Area?

We have several options for tracking an object. What are the options for tracking an object over a large area such as 100mx100m with mm accuracy. Looking for some suggestion of recent...

07 February 2022 7,245 3 View

What is geochemical background value for trace element (Zn, Pb, Cu, Ni, Fe and )Co?

Geochemical background value for trace element is varying for different formation. In hard rock terrain (southern India), geochemical background value will need for geo accumulation calculation.

02 December 2021 5,143 3 View

How to remove soluble copper from the Spent acid/effluent economically?

We are Phthalo Pigment manufacturer. Soluble Copper is present in our by product spent acid. If we remove or reduce the amount of soluble copper from the spent acid, it could be easy to dispose...

03 March 2021 1,135 1 View

How to check spread of AAV2 virus that doesn't express fluorophores?

Hi, I am injecting AAV2-Retro virus (AAV2-retro-EF1a-DIO-FLPo-WPRE-hGHpA from Addgene) that carries cre-dependent flp recombinase, in the mouse dorsal hippocampus and I need to verify that the...

08 November 2020 9,744 3 View

How to solve Inherent Conflict in AR - Challenge in Interaction?

Our recent research shows that AR systems have inherent conflict while interacting with virtual objects. We termed this new conflict as Virtual Kinesthetic Conflict (VKC). This conflict is very...

21 June 2020 5,050 1 View

How to add Cr parameter in autodock?

When I run autogrid4 it says: autogrid4: ERROR: Unknown receptor type: "Cr" -- Add parameters for it to the parameter library first! Look forward to your reply.Thank you so much!

29 July 2024 488 0 View

Do you think Serotonin is Primarily A NEUROTRANSMITTER? Does anyone else like me think this Beautiful Biomarker was repurposed as a Neurotransmitter?

Serotonin (5-hydroxytryptamine, 5-HT) is predominantly known as a neurotransmitter in the central nervous system (CNS), where it plays a crucial role in mood regulation, gastrointestinal motility,...

20 July 2024 3,925 5 View

Information is Stored by Context?

While living in Boston, which has a fine metro system, there were times that I would exit from underground at the wrong location, thereby expecting a particular visual scene only to be momentarily...

17 July 2024 3,237 10 View

Does HEK293T cell express RIG1?

Is there any benefit in knocking out the interferon receptor in 293T cells? In the context of creating RNA viruses 📷

13 July 2024 3,382 0 View

Can i do protein expression of Toll-like receptor 4 cloned in pET-22B in E.coli cell?

Can

08 July 2024 6,725 4 View

Are there any people using biolegend anti- mouse CCR2-BV785?

Hi, I'm working on heart flow cytometry, and I use anti-mouse CCR2-BV785 (biolegend, cat150621) for staining, 20 minutes, 4 degree. But I couldn't see any CCR2+ cells. So I'm not sure if it's...

03 July 2024 3,969 4 View

What are the criterias for Choosing the receptor model (rigid or flexible) in molecular docking?

When choosing the receptor model (rigid or flexible) in molecular docking, does it depend on the designed ligands' characteristics or anything else? For instance: + With the ligand A, the protein...

25 June 2024 2,716 0 View

Is it hard to stain CCR2 for flow cytometry?

Hi, I'm working on the immune cells in the heart and have a problem with CCR2 marker. I did some research and found there's CCR2+ monocytes in heart failure mouse model. When I analysed CCR2...

08 June 2024 7,315 5 View

How can I make complex file of ligand (including flexible residues from protein) with protein Structure after AutodockFR docking?

I have performed the Molecular Docking using ADFR suite, I have obtained the files in _out.pdbqt format for ligand docked poses, upon inspection, both visually and reading the pdbqt files of...

08 June 2024 8,130 2 View

How is it possible to model a protein that consists of several subunits using a Modeller?

Good day, I am trying to model the GABA A receptor, with different subunits. I selected the templates with the highest percent of identity, but as a result of the modeling I got a protein with...

02 June 2024 5,489 2 View