We worked with systolic mitral annulus displacement (SMAD) instead. SMAD is a simple surrogate measure for stroke volume index to detect low-flow low-gradient aortic stenosis with preserved ejection fraction. Longitudinal strain might be another one.
Thanks for your comments. MAPSE ( Mitral Annular Peak Systolic Excursion)/ SMAD does it represent the whole of LV (ejection fraction )especially in calcified aortic stenosis when the annulus too gets calcified.
That MAPSE is representative for global LV performance in low flow/low gradient AS is primarily due to LV hypertrophy.
I have some experience with this. The challenge in evaluating change in LV function before and after TAVI is disentangling true improvement in contractility from simple afterload reduction, so there is no question that speckle tracking strain can easily technically be done pre- and post-TAVI, the key question is, what do changes in strain mean?
Thanks for that update Sumit. Thanks to Darryl for the interesting insight.
for your research work, I can suggest some herbs/medicinal plants fot over healthof henart as well curing some ailmets of circulatory system, you can findout modeof mechanism at cellular/molecular level, ifyou want you canuse bioinformatics for insico screening. So in silico, invitro,inivo all three could be apart of your researh work
Thanks Prof. Ravi Sharma for your suggestion. But unfortunately I am not an independent researcher and I wouldn't be able to carry on with any topic for research. The topic should be associated with my work as I work as a Cardiac Sonographer.That's the reason I am keen in researching the Echocardiographic topics. Anyways I appreciate your time.
http://circ.ahajournals.org/cgi/content/meeting_abstract/126/21_MeetingAbstracts/A17274
We recently published a paper :
C.P. Loizou, S. Petroudi, C.S. Pattichis, M. Pantziaris, A.N. Nicolaides, “An integrated system for the segmentation of atherosclerotic carotid plaque in ultrasound video”, IEEE Trans. Ultras. Ferroel. Freq. Contr., vol. 61, no. 1, pp. 86-101, 2014.
There we investigated the longitudinal and radial strain (movements) of the carotid artery wall and plaque where regions of interest (ROIs) were selected for each CCA video on the first video frame. Specifically, three ROIs, the adventitia wall (AW) at the
near wall, the plaque wall (PW), and the media-adventitia wall (MAW), were selected at the far wall of the CCA. Additioanlly, two ROIs, namely, the maximum plaque border (Pmax) and the minimum plaque border (Pmin) were selected. We used some equations to calculate the radial (RS), longitudinal (LS), and shear strains (SS) from the radial and longitudinal displacement indices. All above metrics may completely and reliably describe longitudinal and radial strain.
Here is a link showing an advantage of using strain during post-TAVI evaluation of the patient. Basically, LV GLS shall improve >1.5% to be sure that the patient has a good prognosis.
bit.ly/2j5wpmM
I assume this is echo based GLS, I have experience in CMR and echo based GLS, and I can say results are really reproducible in CMR which is really important in this analysis. However, I can't say the same thing for echo based one, particularly after replacement it's getting harder to see endocardial borders.
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