My lab recently started using Myomerger, transferring direct ratios from cells to mice caused the death of all treated mice within a few hours of injection.

The department involved want to brute force the issue instead of titrating to reach a non-lethal dosage, i feel bad for the mice and would like to find some paper or figure to give them a upper dosage to avoid.

i couldn't find anything definitive online, anyone have something on the subject?