What aspects you are talking!? The ring shape stereochemistry is there owing to the non-aromatic bonds of the rings available in the product. If all rings are fully aromatic, they will be flat, with some contribution from the heterocyclic atom, it would be better for you to make a model of your compounds and do the bond angle mapping. For synthesis, it depends upon the starting material, and any role a catalyst might have. Your question is very vague and needs a more specific query.

Efficient Synthesis and Antimicrobial Evaluation of Pyrazolopyranopyrimidines in the Presence of SBA-Pr-SO3H as a Nanoporous Acid Catalyst. - Abstract - Europe PMC

Dear Dharmendra Gehlot thank you for posting this interesting technical question. As a synthetic inorganic chemist I'm absolutely not an expert about this class of compounds. However, I made the long-time experience that a lot of useful information can be found and accessed right here on this platform. Just search RG for the term "pyrazolopyranopyrimidines" and then click on "Publications". This will provide you with a list of all relevant articles about this topic which have been posted by RG members, many of them even as freely accessible public full texts:

https://www.researchgate.net/search.Search.html?type=researcher&query=Pyrazolopyranopyrimidines

As a typical example please have a look at the following interesting article:

Pyrazolopyranopyrimidines as a Class of Anti-Inflammatory Agents

Article Pyrazolopyranopyrimidines as a Class of Anti-Inflammatory Agents

Good luck with your research and best wishes, Frank Edelmann

Here are some lead references that may help:

Synthesis of Novel Acidic Ionic Liquid [BBSA-DBU][HSO4] and Its Catalytic Activities for Synthesis of Pyrazolopyranopyrimidine Derivatives. Patil, M.; Shinde, S.; Damate, S.; Patil, S. Asian Journal of Chemistry 2018, 30(5), 961–966 DOI: 10.14233/ajchem.2018.21028

An Efficient Four Component Domino Synthesis of Pyrazolopyranopyrimidines using Recyclable Choline Chloride:Urea Deep Eutectic Solvent. Tipale, Madhuri R.; Khillare, Lalit D.; Deshmukh, Amarsinh R.; Bhosle, Manisha R. Journal of Heterocyclic Chemistry 2018, 55(3), 716–728 DOI: 10.1002/jhet.3095

Asymmetric [4 + 2] Annulation Reactions Catalyzed by a Robust, Immobilized Isothiourea. Wang, Shoulei; Izquierdo, Javier; Rodríguez-Escrich, Carles; Pericàs, Miquel A. ACS Catalysis 2017, 7(4), 2780–2785 DOI: 10.1021/acscatal.7b00360

Synthesis of pyranopyrazolo N-glycoside and pyrazolopyranopyrimidine C-glycoside derivatives as promising antitumor and antimicrobial agents. Hafez, Hend N.; El-Gazzar, Abdel-Rhman B. A. Acta Pharmaceutica 2015, 65, 215–233 DOI: 10.1515/acph-2015-0022