I want to study the sorption and desorpotion of an antibiotic by microplastics in the gut of a marine fish species. I'm wondering if I can prepare a solution that is extremely similar to the intestinal environment (simialr pH, compotiosion of ions, disgest enzymes and etc), and then do the kinetics test in that solution? Has anyone done a similar study of this? Could you kindly share the protocol to prepare the "intestinal environment-like solution"?

(I speculated that the intestinal contents in fish are more like liquid than a solid? Am I wrong?)

Thanks in advance!