Few days ago, it was announced that researchers in China reported the first visualisation of a hydrogen bond using atomic force microscopy (AFM).In May, Felix Fischer and colleagues at the University of California Berkeley in the US used AFM to image molecules before and after a chemical transformation. The remarkable images showed the formation of covalent bonds in a cyclisation reaction.

In the latest study to visualise molecules, Xiaohui Qiu and colleagues at the National Centre for Nanoscience and Technology, China, went one step further. They used the same non-contact AFM as Fischer, but instead of looking for covalent bonds they tweaked it to look for weaker interactions.

Do you think we had reached the limit of magnification or we can see bigger molecule soon?

http://www.rsc.org/chemistryworld/2013/09/first-pictures-hydrogen-bonds-unveiled-afm

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