I recommend you write to Dr. Jairo Useche Vivero, researcher in numerical simulation area of the Technological University of Bolivar: [email protected]
For the material under consideration, stress - life curve needs to be obtained experimentally. For the well established materials, it may be available in literature. For newer materials, it needs to be generated. Based on this, fatigue analysis of the structure can be performed.
Some indirect measurements can give useful insight into stress-life curve. Please look into the link: http://asm.matweb.com/search/SpecificMaterial.asp?bassnum=MTP641
Given fatigue strength and a bunch of mechanical properties, some guess can be made.