Dear network!

I have a question and hope that you will share with me your experience in this field.

We have conducted a study (review of patients medical records) to assess if abnormal hemoglobin (Hb) levels are associated with stroke severity in our settings. We are interested in both; high and low Hb levels. As for me, I though the right thing is to dichotomize Hb levels into normal and abnormal status in the Regression Analysis. Upon submitting the work to a journal, the reviewers mentioned that Hb levels should have been continuous variable. As both extreme can be a determinant of stroke severity, how the results would be interpreted in this way!

Thank you for your time, Majeda

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