It is known that embryos can survive for a limited age in vitro and cannot proceed to organogenesis because lack of placentation and unlimited factors in the uterine and maternal environment.
Two recent studies reported culture of human embryos for long periods in order to explore the early embryonic development, stem cell differentiation and organogenesis (Deglincerti et al., 2016; Shahbazi et al., 2016); doi:10.1038/nature17948 & doi: 10.1038/ncb3347
In our recent paper;
https://www.researchgate.net/publication/317646943_Isolation_and_characterization_of_the_trophectoderm_from_the_Arabian_camel_Camelus_dromedarius
we found that in vivo flushed embryos can survive in vitro for 25 days post-insemination and embryo-derived cells showed growth and expansion . And this is the longest period recorded according to our knowledge.
I think a better culture conditions to enable culturing human embryos beyond the 14-day, will be more realistic than culturing isolated stem cells individually. The communication among different embryonic stem cells shall not be ignored.
Article Isolation and characterization of the trophectoderm from the...
Hello dear
see
https://bmcmedethics.biomedcentral.com/articles/10.1186/s12910-017-0198-5
I would like to share the recently published article in "Development" entitled "The status of the human embryo in various religions"
http://dev.biologists.org/content/144/14/2541
The Conclusion of this paper:
Some religions embrace the belief that an early embryo in vitro constitutes a person, but this belief is not a universal ethical principle. In general, the Roman Catholic Church is the strongest proponent of this belief, and thus, not surprisingly, has in recent decades opposed the artificial creation and use of human embryos and human embryonic stem cells in every form. While a diversity of views can and does exist in every religion, as a general theme it is clear that other major religions such as Judaism, Islam, Buddhism, and some Protestant denominations reject the idea that an embryo prior to implantation in a uterus is a person, and thus are, in general, more supportive of research into human embryology.
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