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Questions related from Zoppoli Gabriele
We're going to run a 100 some 8x60k GE arrays on material that is OCT-embedded and frozen, degraded a bit though (rectal samples): any suggestion for what's best for hybridization? We have both...
10 October 2013 2,585 0 View
I was wondering if anyone knows whether there is any package to plot figures with a given gene, its domains, and symbols from a list of pre-specified mutations, something like what is seen in the...
08 August 2013 1,163 3 View
Hi all, I basically want to annotate all known SNVs on the CDH1 coding region, on scale. Any easy way to do that that doesn't involve a "learn SVG and do Illustrator" answer? Please see attached...
04 April 2013 9,005 0 View
I'm trying to go through the supplementary material of Shah's Nature paper 2012 on triple negative breast cancer genomics. Apart from the tricky annotations (hg18 and discontinued gene symbols), I...
03 March 2013 6,401 12 View
I would like to annotate a 3D protein structure with its domains and mutated/altered aminoacids and produce a nice looking, high quality picture for publication purposes. Does anyone have any...
02 February 2013 2,015 1 View
Let's say I ran forty cancer samples, twenty responders and twenty non-responders to some treatment. I performed alignment and annotation of SNVs and indels in each sample. Now I want to know if...
11 November 2012 9,730 12 View
I'm curious to find out which genes show an extremely biased AT content in human beings (i.e., within the same species, not compared to other ones). Any clue how I might find that out?
10 October 2012 4,769 5 View
We have very small samples from snap-frozen biopsies and need to perform several analyses with them. I have been against preamplification, since I'm afraid it would introduce more bias in an...
10 October 2012 5,638 15 View