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Seperating cytoplasmic and nuclear protein is usually conducted for studing protein distribution, especially transcrition factors, by western blotting. Tubulin is the most used cytoplasmic marker...
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ATM is mutated in A-T patients. And A-T patients are always with a higher risk of cancer. But the status of ATM in the established cancer cell lines is seldom described. Dose anybody know which...
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With the increasing studies of microRNAs, more and more research reported that a specific miRNA could target multiple targets of a signaling pathway of related pathways. In some of these papers,...
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I am working to find out which transcription factors (TFs) may binding to my target gene’s promoter to regulate its expression. In the past, I used the ConSIte web site to find the potential TFs...
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Recently, I detected the expression of a miRNA by Q-PCR. The Ct values for triplicates are exactly the same,Ct=35.0, given by the computer, howerve I noticed that in fact there was a little...
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I thought tumor-initiating cells are crucial in tumor initiating as it names and cancer stem cells are essential for maintenance of the population of cancer cells and account for treatment...
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