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A published paper mentioned that DOTAP liposomal transfection reagent could deliver RNA to endosomes. Does lipo 3000, lipo 2000, RNAiMax can achieve the same results? Thanks.
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According to several published papers，I added 400 mM HFIP in the mobile phase to increase the intensity of oligonucleotides in LC-ESI-TOFMS. However, the intensity of HFIP (m/z 166.9983 [M-H]- and...
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I prepare to analyze oligonucleotides' fragments (4-12 nt) by MALDI TOF/TOFMS. I used trihydroxyacetophenone as matrix and the concentration of sample was approximately 5 ng/ul. The performance of...
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The limits of quantification (LOQ) is defined as 10 times of the signal to noise ratio (S/N). I prepare a standard solution for HPLC analysis and dilute several times to S/N≈10 as LOQ. What about...
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