Y. Kuthati

5 Questions 7 Answers 0 Followers

Questions related from Y. Kuthati

Intrathecal delivery of a drug in Rats?

How to improve solubility of poorly soluble drugs for intrathecal delivery

14 November 2017 3,851 0 View

What is the best way to link Rhodamine 110 dye with Chitosan polymer?

I want to link Rhodamine 110 dye with chitosan polymer and use it for coating over inoganic nanomaterials with amine functional groups through EDC/NHS chemistry. What is the best way to graft...

05 May 2016 4,846 2 View

Is there any reaction to bond Amine (-NH2) groups to Hydroxyl (-OH) groups?

I want to bind Hydroxyl group containing drugs like Vanillic acid and Gallic acid in to the internal pores of amine (3-Aminopropyl)triethoxysilane) modified mesoporous silica nanoparticles. Can...

25 April 2016 195 4 View

Immobilization of Hydroxyl group drugs inside the Mesoporous silica nanoparticles with acid labile link for pH sensitive release?

Could any one please suggest to me the most apt acid labile chemical bond (ortho ester, ester, imine, hydrazone, cis aconityl, acetal/ketal) for immobilization of drugs with high number of...

28 March 2016 1,511 0 View

Are anti-oxidants capable of harvesting ROS even without release from the nanocarriers if the naocarriers are targeted to the site of ROS?

I am planning to immobilize anti-oxidants like Gallic acid in a nanocarrier with targeting moiety decorated on the surface of the nanocarrier. If i link the anti-oxidant with a covalent bond is it...

21 March 2016 8,534 7 View