William M McFadden

5 Questions 1 Answers 0 Followers

Questions related from William M McFadden

Easist way to prepare a .pdb file of an icosahedral capsid assembly from the monomeric protein coordinates?

I'd like to make a nice molecular model of the theoretical assembly of an icosahedral viral capsid in chimeraX from the structure of a monomer. I do not think chimera can do this alone, but how...

22 March 2025 2,494 1 View

Is there a proper citation for the human genome assemblies?

I am currently writing up results from a study that utilized the hg19 [Genome Reference Consortium Human Build 37 (GRCh37)] for analysis and I have not been able to identify a way to cite this...

25 November 2020 10,238 2 View

Is there a BLAST package that supports a Custom Matrix?

There is a published substitution matrix for intrinsically disordered proteins that I would like to use for a BLAST search, but I am unable to find a program that supports uploading a custom...

03 February 2020 8,255 2 View

How to do GO-term analysis in R from a list of genes?

I am using R/R-studio to do some analysis on genes and I want to do a GO-term analysis. I currently have 10 separate FASTA files, each file is from a different species. Is there a way in R to use...

22 January 2020 6,584 1 View

Are there antibodies that can distinguish between a protein monomer and a protein dimer?

Does anyone know of an antibody that can distinguish between a protein in a monomeric vs a dimeric state? This question is in regards to a homodimer (or homomultimer) complex. Any examples would...

01 January 1970 1,543 3 View