Werner Pfeifer

6 Questions 8 Answers 0 Followers

Questions related from Werner Pfeifer

10-year survival rates for BRCA1 carriers with BC?

Hello everybody, does somebody know an overview about 5- oder 10-year survival rates for BRCA1 mutation carriers with BC? I have read a paper from Huzarski 2013, but I would like to know more...

16 April 2016 6,845 1 View

Why are CHEk2-mutated breast tumors are so chemoresistant?

Hello everybody, CHEK2-related breast cancers are very chemoresistant. Can somebody explain me, why they are so chemoresistant? Anthracyclines are not working here compared to...

11 April 2016 7,197 2 View

Why BRCA1-cancer patient cohorts have to be <50 years of age?

Hello everybody, can somebody explain me, why there is a borderline in many studies that patients in neoadjuvant BRCA1-cohorts have to be younger than 50 years of age? Is there some literature...

11 April 2016 7,436 2 View

Loss of staging information (cancer therapy)?

Hello everybody, during my research for information about neoadjuvant therapy, I have found a powerpoint presentation with the following information: "Chemonaive tumors are very informative for...

01 April 2016 1,271 3 View

Does someone knows a good book or a PDF file on the subject of DNA repair? Especially with BRCA1 as a key gene?

Does someone knows a good book or a PDF file on the subject of DNA repair? Especially with BRCA1 as a key gene? It is for a thesis defence. So it shouldn't be too extensive.

16 March 2016 1,523 7 View

What are the current (and hopefully complete) recommendations for treatment of BRCA1-associated breast and ovarian cancer?

Hello everybody, I need some good paper/other literature to be prepared for my thesis defence soon. My thesis was about hereditary breast cancer and neoadjuvant therapy. Best wishes, Werner

07 January 2016 6,138 2 View