V. A. Aniol

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Questions related from V. A. Aniol

Can rat and mouse brain respond differently to systemic LPS?

Is it possible that rats and mice differ in their susceptibility to LPS (E.coli) effects? We have mentioned serious microglial activation in the brain (increase in the number and cell area of...

05 May 2014 157 5 View

Is it possible that the same antibodies do not work on floating sections but stain well on paraffin-embedded tissue?

My iNOS antibodies did not stain anything on rat brain floating sections (fixed in 4% CH2O and cut in 50 um thick) from different models where neuroinflammation is well documented (including focal...

05 May 2014 2,717 16 View

Has somebody observed microglial activation in the rat brain after systemic LPS?

Does somebody have experience in inducing the microglial activation by systemic LPS injection in rats? Mice seem to respond well to LPS, but rat do not demonstrate neuroinflammatory changes in...

05 May 2014 2,978 2 View