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Questions related from Srinivasa Rao Penumutchu
I have macro (abs.13c) from one of my friend that she got from bruker to correct the baseline after processing the 1d spectra. could you please let me know that How to install user defined macro...
03 May 2017 7,619 3 View
Does anyone know how I can set up the zgesfpgp 1d experiment (flipback water gate) on bruker? I am looking for p29 duration to set up the 1D experiment. We look at pulse sequence file for the...
11 February 2015 9,718 3 View
The binding affinity between the protein and the fluroscent ligand derived from fluorescence experiments was in the millimolar range 0.18 mM ( 180 Micro molar). Unfortunately we did not get the...
28 May 2014 486 4 View
We finished HSQC titration experiments for protein-protein complex (A-B) and observed the line broadening at the interface of the binding interface of the both proteins .The peak signal is not...
01 December 2013 9,784 11 View
We solved the crystal structure for chemical compound and have got a structure in cif file format. Could you please let me know if there is any web-server or software to convert the cif file to PDB?
31 October 2013 7,055 22 View
We would like to generate the crystal coordinates file for the drug, which crystal structure has been solved, but they didn't submit coordinates in any database. The bond angles and bond lengths...
09 September 2013 1,270 6 View
We are calculating the protein A - protein B complex structure , Binding interface of the complex is validating the by construct the mutants on interface of protein A , Other-side most of the...
15 July 2013 5,967 2 View
I am calculating the structure of the protein-protein complex. Binding interface of protein complex is validating by mutagenesis experiments. We constructed a triple mutant protein which...
17 June 2013 9,423 2 View
I would like to take TEM images for protein complex , complex size is around 85 Kd , Could you please let me know that what is size limitation for protein complex to take TEM images ? please...
11 December 2012 8,426 1 View
what is best way to validate protein complex which is solved by HADDOCK by using chemical shift perturbation data (NMR) or any other docking program ?
18 October 2012 7,451 3 View
Is their any software or web server available to calculate the binding constant and enthalpy of protein-protein interaction?
11 September 2012 2,571 16 View
How can we distinguish between a crystallographic dimer and a non-crystallographic dimer ?. When studying the 3C protease protein across different viruses, researchers often observe dimeric...
01 January 1970 1,189 4 View
