Showande Johnson Segun

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Questions related from Showande Johnson Segun

I would like to know the normal values of hematological & biochemical parameters in Albino rats. Can someone help with pdf/link containing the values?

I conducted acute and subacute oral toxicity tests in Albino rats focusing on hematological and biochemical toxicities. Some of the values obtained in the treatment group were significantly...

08 April 2018 5,780 4 View

What is the best form of pharmacokinetic analysis of Simvastatin?

Should I use Non-Compartmental Analysis or Compartmental Analysis? If Compartmental analysis, should it be 1or2 compartment model and why?

04 July 2016 4,808 3 View

Does anyone know what the cut-off point for hyperlipidemia is in rats based on cholesterol, triglyceride, LDL, and HDL?

I am inducing hyperlipidemia in rats and I want to be sure when to say they are already hyperlipidemic. Are the values for lipid profile same as in human? I am confused with what I have found so...

25 November 2013 4,537 0 View

How can I induce hypercholesterolemia in rats without using cholesterol? Is there oil/food that is rich in cholesterol and available in Nigeria?

It is difficult to get a high fat rat diet in Nigeria. Do you know of any oil/food that is rich in cholesterol and available here?

20 November 2013 8,884 7 View

How do you write or phrase your ethical consideration for a study without ethical approval, in order for it to be acceptable in high impact journals?

I conducted a study on screening for cardiovascular disease risk factors which partly involved checking glucose and cholesterol level in participants using Point of Care Test kits. When the study...

26 September 2013 4,354 12 View

Is it necessary to concentrate a polyherbal liquid preparation in a toxicity study, or can I use ml/kg body weight in rats?

For a sub-chronic toxicity study of liquid poly-herbal formulation in rats, can I use the preparation without concentrating with doses as ml/kg, instead of concentrating it and using mg/kg body...

21 February 2013 1,382 17 View

Which sex of rat is suitable for an acute and a subchronic toxicity test?

Animal toxicity test for poly herbal formulations.

18 February 2013 5,908 6 View