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Questions related from Shankar Subramanian
A 30 year old lady tested positive for HIV in 2011 during routine antenatal check up of her first pregnancy. The patient confirmed the same from multiple other laboratories as is the norm (most...
28 September 2017 1,703 5 View
28 September 2017 990 4 View
55 year old male with Psoriasis and Psoriatic arthritis was not responding to methorexate alone. He was screened for LTBI (mantoux and Quantiferon TB Gold), found negative and started on TNF...
19 February 2017 6,095 9 View
This 18 year old girl was detected to have Takayasu arteritis with hypertension during evaluation for polyarthralgias. MR angiography revealed her to have severe renal artery stenosis left and...
25 January 2016 9,346 8 View
I have a young 26 year old male patient with active ankylosing spondylitis (predominantly axial, HLA B27 positive). With his current disease activity, he is eligible for anti TNFs. However he was...
30 December 2015 332 18 View
Atheromatous plaques are commonly seen in the coronaries, carotids and aorta. Despite sharing the same risk factors only certain sites are predisposed. Even in the same individual, despite similar...
07 December 2015 8,107 9 View
We have a 21 year old girl who has been symptomatic for last 3 months with polyarthritis and multiple cutaneous ulcers over lower limbs with hemorrhagic blisters. She thereafter developed multiple...
04 December 2015 8,649 7 View
For the last 2 decades we have seen a spate of clinical trials for different biologic agents starting from anti TNF agents (etanercept/Infliximab/adalimumab/golimumab), T cell costimulation...
22 November 2015 2,603 15 View
A 42 year old male died of Sudden Cardiac Death after running 6 Km on a treadmill at a Gym. He was a regular runner who ran 6-8 Km daily and the marathon 1-2 times a year. His BMI was 24 and a...
13 November 2015 6,916 14 View
I recently came across a 60 year old lady who had been treated for HCV infection. She was documented during evaluation to have low serum immunoglobulins and the Immunoglobulin profile showed low...
06 October 2015 2,947 5 View
About 2%-4% patients fail the first line therapy every year in India, mostly related to adherence issues. Testing shows them to have resistance to the NRTIs and NNRTIs. Would it be acceptable to...
23 September 2015 1,460 4 View
During the practice of HIV care, I have often come across this curious phenomenon of Immunovirological discordance. Here the patient comes with a falling CD4 count over time but the plasma viral...
12 September 2015 1,422 11 View
The START (“Strategic Timing of AntiRetroviral Treatment”) study was a randomized, controlled clinical trial designed to more clearly define the optimal time for HIV- infected individuals to begin...
19 August 2015 3,119 5 View
